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Lara Adnan Aqrawi

- Associate Professor
Institutt for helse og trening
School of Health Sciences

LaraAdnan.Aqrawi@kristiania.no

+47 413 13 784

Employee details

Scientific Publications
Hynne, Håvard, Aqrawi, Lara A., Jensen, Janicke Liaaen, Thiede, Bernd, Palm, Øyvind, Amdal, Cecilie Delphin, Westgaard, Kristine Løken, Herlofson, Bente Brokstad, Utheim, Tor Paaske & Galtung, Hilde (2022). Proteomic Profiling of Saliva and Tears in Radiated Head and Neck Cancer Patients as Compared to Primary Sjögren’s Syndrome Patients. International Journal of Molecular Sciences. ISSN 1661-6596. 23(7) doi:
10.3390/ijms23073714

Khatri, Bhuwan, Tessneer, Kandice L., Rasmussen, Astrid, Aghakhanian, Farhang, Reksten, Tove Ragna, Adler, Adam, Alevizos, Ilias, Anaya, Juan-Manuel, Aqrawi, Lara A., Baecklund, Eva, Brun, Johan Gorgas, Bucher, Sara Magnusson, Eloranta, Maija-Leena, Engelke, Fiona, Forsblad-d’Elia, Helena, Glenn, Stuart B., Hammenfors, Daniel, Imgenberg-Kreuz, Juliana, Jensen, Janicke Liaaen, Johnsen, Svein Joar Auglæn, Jonsson, Malin Viktoria, Kvarnström, Marika, Kelly, Jennifer A., Li, He, Mandl, Thomas, Martín, Javier, Nocturne, Gaétane, Norheim, Katrine Brække, Palm, Øyvind, Skarstein, Kathrine, Stolarczyk, Anna M., Taylor, Kimberly E., Teruel, Maria, Theander, Elke, Venuturupalli, Swamy, Wallace, Daniel J., Grundahl, Kiely M., Hefner, Kimberly S., Radfar, Lida, Lewis, David M., Stone, Donald U., Kaufman, C. Erick, Brennan, Michael T., Guthridge, Joel M., James, Judith A., Scofield, R. Hal, Gaffney, Patrick M., Criswell, Lindsey A., Jonsson, Roland, Eriksson, Per, Bowman, Simon J., Omdal, Roald, Rönnblom, Lars, Warner, Blake, Rischmueller, Maureen, Witte, Torsten, Farris, A. Darise, Mariette, Xavier, Alarcon-Riquelme, Marta E., Shiboski, Caroline H., Herlenius, Marie Elisabeth Wahren, Ng, Wan-Fai, Sivils, Kathy L., Adrianto, Indra, Nordmark, Gunnel & Lessard, Christopher J. (2022). Genome-wide association study identifies Sjögren’s risk loci with functional implications in immune and glandular cells. Nature Communications. ISSN 2041-1723. 13(1) p 1-17. doi:
10.1038/s41467-022-30773-y

Lundtoft, Christian, Pucholt, Pascal, Martin, Myriam, Bianchi, Matteo, Lundström, Emeli, Eloranta, Maija-Leena, Sandling, Johanna K., Sjöwall, Christopher, Jönsen, Andreas, Gunnarsson, Iva, Rantapää-Dahlqvist, Solbritt, Bengtsson, Anders A., Leonard, Dag, Baecklund, Eva, Jonsson, Roland, Hammenfors, Daniel, Forsblad-d'Elia, Helena, Eriksson, Per, Mandl, Thomas, Magnusson Bucher, Sara, Norheim, Katrine Brække, Johnsen, Svein Joar Auglæn, Omdal, Roald, Kvarnström, Marika, Wahren Herlenius, Marie Elisabeth, Notarnicola, Antonella, Andersson, Anna Helena, Molberg, Øyvind, Diederichsen, Louise Pyndt, Almlöf, Jonas, Syvänen, Ann-Christine, Kozyrev, Sergey V., Lindblad-Toh, Kerstin, Nilsson, Bo, Blom, Anna M., Lundberg, Ingrid E., Nordmark, Gunnel, Diaz-Gallo, Lina-Marcela, Svenungsson, Elisabet, Rönnblom, Lars, Brun, Johan G., Brokstad, Karl Albert, Skarstein, Kathrine, Jonsson, Malin Viktoria, Appel, Silke, Aqrawi, Lara A., Jensen, Janicke Liaaen, Palm, Øyvind & Kämpe, Olle (2022). Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases. Arthritis & Rheumatology. ISSN 2326-5191. 74(8) p 1440-1450. doi:
10.1002/art.42122

Westgaard, Kristine Løken, Hynne, Håvard, Amdal, Cecilie Delphin, Young, Alix, Singh, Preet Bano, Chen, Xiangjun, Rykke, Morten, Hove, Lene Hystad, Aqrawi, Lara A., Utheim, Tor Paaske, Herlofson, Bente Brokstad & Jensen, Janicke Liaaen (2021). Oral and ocular late effects in head and neck cancer patients treated with radiotherapy. Scientific Reports. ISSN 2045-2322. 11:4026 p 1-11. doi:
10.1038/s41598-021-83635-w

Bharaj, Tamandeep Kaur, Aqrawi, Lara A., Fromreide, Siren, Jonsson, Roland, Brun, Johan G., Appel, Silke & Skarstein, Kathrine (2021). Inflammatory Stratification in Primary Sjögren’s Syndrome Reveals Novel Immune Cell Alterations in Patients’ Minor Salivary Glands. Frontiers in Immunology. ISSN 1664-3224. 12 p 1-16. doi:
10.3389/fimmu.2021.701581

Samuelsen, Tea Marie B, Aqrawi, Lara A., Skarstein, Kathrine & Jensen, Janicke Liaaen (2021). Evaluering av spyttkjertelbiopsier ved utredning av Sjögrens syndrom. Den norske tannlegeforenings tidende. ISSN 0029-2303. 131 p 988-994.
Tashbayev, Behzod, Garen, Torhild Oddveig, Palm, Øyvind, Chen, Xiangjun, Herlofson, Bente Brokstad, Young Vik, Alix Rosslyn, Hove, Lene Hystad, Rykke, Morten, Singh, Preet Bano, Aqrawi, Lara Adnan, Utheim, Øygunn Aass, Utheim, Tor Paaske & Jensen, Janicke Cecilie Liaaen (2020). Patients with non-Sjögren's sicca report poorer general and oral health-related quality of life than patients with Sjögren's syndrome: a cross-sectional study. Scientific Reports. ISSN 2045-2322. doi:
10.1038/s41598-020-59078-0

Aqrawi, Lara Adnan, Jensen, Janicke Cecilie Liaaen, Fromreide, Siren, Galtung, Hilde Kanli & Skarstein, Kathrine (2020). Expression of NGAL-specific cells and mRNA levels correlate with inflammation in the salivary gland, and its overexpression in the saliva, of patients with primary Sjögren’s syndrome. Autoimmunity. ISSN 0891-6934. p 1-11. doi:
10.1080/08916934.2020.1795140

Aqrawi, Lara A., Chen, Xiangjun, Hynne, Håvard, Amdal, Cecilie Delphin, Reppe, Sjur, Aass, Hans Christian Dalsbotten, Rykke, Morten, Hove, Lene Hystad, Young, Alix, Herlofson, Bente Brokstad, Westgaard, Kristine Løken, Utheim, Tor Paaske, Galtung, Hilde & Jensen, Janicke Liaaen (2020). Cytokines Explored in Saliva and Tears from Radiated Cancer Patients Correlate with Clinical Manifestations, Influencing Important Immunoregulatory Cellular Pathways. Cells. ISSN 2073-4409. 9(9) doi:
10.3390/cells9092050

Thorlacius, Gudny Ella, Hultin-Rosenberg, Lina, Sandling, Johanna K., Bianchi, Matteo, Imgenberg-Kreuz, Juliana, Pucholt, Pascal, Theander, Elke, Kvarnström, Marika, Forsblad-d’Elia, Helena, Bucher, Sara Magnusson, Norheim, Katrine Brække, Johnsen, Svein Joar Auglænd, Hammenfors, Sten Daniel, Skarstein, Kathrine, Jonsson, Malin V, Bäcklund, Eva, Aqrawi, Lara A., Jensen, Janicke Liaaen, Palm, Øyvind, Morris, Andrew P., consortium, the DISSECT, meadows, jennifer r, Rantapää-Dahlqvist, Solbritt, Mandl, Thomas, Eriksson, Per, Lind, Lars, Omdal, Roald, Jonsson, Sten Ture Roland, Lindblad-Toh, Kerstin, Rönnblom, Lars, Wahren-Herlenius, Marie & Nordmark, Gunnel (2020). Genetic and clinical basis for two distinct subtypes of primary Sjögren's syndrome. Rheumatology. ISSN 1462-0324. 60(2) p 837-848. doi:
10.1093/rheumatology/keaa367

FULLTEKST

Chen, Xiangjun, Aqrawi, Lara Adnan, Utheim, Tor Paaske, Tashbayev, Behzod, Utheim, Øygunn Aass, Reppe, Sjur, Hove, Lene Hystad, Herlofson, Bente Brokstad, Singh, Preet Bano, Palm, Øyvind, Galtung, Hilde & Jensen, Janicke Liaaen (2019). Elevated cytokine levels in tears and saliva of patients with primary Sjögren's syndrome correlate with clinical ocular and oral manifestations. Scientific Reports. ISSN 2045-2322. 9(1) doi:
10.1038/s41598-019-43714-5

Aqrawi, Lara Adnan, Galtung, Hilde, Guerreiro, Eduarda, Øvstebø, Reidun, Thiede, Bernd, Utheim, Tor Paaske, Chen, Xiangjun, Utheim, Øygunn Aass, Palm, Øyvind, Skarstein, Kathrine & Jensen, Janicke Liaaen (2019). Proteomic and histopathological characterisation of sicca subjects and primary Sjögren’s syndrome patients reveals promising tear, saliva and extracellular vesicle disease biomarkers. Arthritis Research & Therapy. ISSN 1478-6354. 21 p 1-14. doi:
10.1186/s13075-019-1961-4

Skarstein, Kathrine, Jensen, Janicke Liaaen, Galtung, Hilde, Jonsson, Roland, Brokstad, Karl Albert & Aqrawi, Lara A. (2019). Autoantigen-specific B cells and plasma cells are prominent in areas of fatty infiltration in salivary glands of patients with primary Sjogren?s syndrome. Autoimmunity. ISSN 0891-6934. 52 p 242-250. doi:
10.1080/08916934.2019.1684475

Aqrawi, Lara Adnan, Ivanchenko, M., Björk, Annette, Ramirez Sepúlveda, Jorge I., Imgenberg-Kreuz, Juliana, Kvarnström, M, Haselmayer, P., Jensen, Janicke Liaaen, Nordmark, G, Chemin, K., Skarstein, Kathrine & Wahren-Herlenius, M. (2018). Diminished CXCR5 expression in peripheral blood of patients with Sjogren's syndrome may relate to both genotype and salivary gland homing. Clinical and Experimental Immunology. ISSN 0009-9104. 192(3) p 259-270. doi:
10.1111/cei.13118

Aqrawi, Lara Adnan, Jensen, Janicke Liaaen, Øijordsbakken, Gunnvor, Ruus, Ann-Kristin, Nygård, Ståle, Holden, Marit, Jonsson, Roland, Galtung, Hilde & Skarstein, Kathrine (2018). Signalling pathways identified in salivary glands from primary Sjögren's syndrome patients reveal enhanced adipose tissue development. Autoimmunity. ISSN 0891-6934. 51(3) p 135-146. doi:
10.1080/08916934.2018.1446525

Aqrawi, Lara Adnan, Chen, Xiangjun, Jensen, Janicke Liaaen, Morthen, Mathias Kaurstad, Thiede, Bernd, Utheim, Øygunn Aass, Palm, Øyvind, Tashbayev, Behzod, Utheim, Tor Paaske & Galtung, Hilde (2018). Severity of clinical dry eye manifestations influences protein expression in tear fluid of patients with primary Sjögren's syndrome. PLOS ONE. ISSN 1932-6203. 13:e0205762(10) p 1-14. doi:
10.1371/journal.pone.0205762

Aqrawi, Lara Adnan, Galtung, Hilde, Vestad, Beate, Øvstebø, Reidun, Thiede, Bernd, Rusthen, Shermin, Young, Alix, Guerreiro, Eduarda, Utheim, Tor Paaske, Chen, Xiangjun, Utheim, Øygunn Aass, Palm, Øyvind & Jensen, Janicke Liaaen (2017). Identification of potential saliva and tear biomarkers in primary Sjögren’s syndrome, utilising the extraction of extracellular vesicles and proteomics analysis. Arthritis Research & Therapy. ISSN 1478-6354. 19(1) doi:
10.1186/s13075-017-1228-x

Rusthen, Shermin, Young, Alix, Herlofson, Bente Brokstad, Aqrawi, Lara Adnan, Rykke, Morten, Hove, Lene Hystad, Palm, Øyvind, Jensen, Janicke Liaaen & Singh, Preet Bano (2017). Oral disorders and oral health-related quality of life in patients with primary Sjögren’s Syndrome. European Journal of Oral Sciences. ISSN 0909-8836. 125(4) p 265-271. doi:
10.1111/eos.12358

Tashbayev, Behzod, Rusthen, Shermin, Young, Alix, Herlofson, Bente Brokstad, Hove, Lene Hystad, Singh, Preet Bano, Rykke, Morten, Aqrawi, Lara Adnan, Chen, Xiangjun, Utheim, Øygunn Aass, Utheim, Tor Paaske, Palm, Øyvind & Jensen, Janicke Liaaen (2017). Interdisciplinary, comprehensive oral and ocular evaluation of patients with primary Sjögren's syndrome. Scientific Reports. ISSN 2045-2322. 7:10761 p 1-9. doi:
10.1038/s41598-017-10809-w

Szyszko, Ewa Alicja, Aqrawi, Lara Adnan, Jonsson, Roland, Brokstad, Karl Albert & Skarstein, Kathrine (2016). Non-proliferating plasma cells detected in the salivary glands and bone marrow of autoimmune NOD.B10.H2b mice, a model for primary Sjögrens syndrome. Autoimmunity. ISSN 0891-6934. 49(1) p 41-49. doi:
10.3109/08916934.2015.1079820

Skarstein, Kathrine, Aqrawi, Lara Adnan, Øijordsbakken, Gunnvor, Jonsson, Roland & Jensen, Janicke Liaaen (2016). Adipose tissue is prominent in salivary glands of Sjögren’s syndrome patients and appears to influence the microenvironment in these organs. Autoimmunity. ISSN 0891-6934. 49(5) p 338-346. doi:
10.1080/08916934.2016.1183656

Voltersvik, Pål, Aqrawi, Lara Adnan, Dudman, Susanne Gjeruldsen, Hungnes, Olav, Bostad, Leif, Brokstad, Karl Albert & Cox, Rebecca Jane (2016). Pulmonary changes in Norwegian fatal cases of pandemic influenza H1N1 (2009) infection: a morphologic and molecular genetic study. Influenza and Other Respiratory Viruses. ISSN 1750-2640. 10(6) p 525-531. doi:
10.1111/irv.12410

FULLTEKST

Sjöstrand, Maria, Johansson, Alina, Aqrawi, Lara Adnan, Olsson, Tomas, Wahren-Herlenius, Marie & Espinosa, Alexander (2016). The expression of BAFF is controlled by IRF transcription factors. Journal of Immunology. ISSN 0022-1767. 196(1) p 91-96. doi:
10.4049/jimmunol.1501061

Trondsen, Monica, Aqrawi, Lara Adnan, Zhou, Fan, Pedersen, Gabriel Kristian, Trieu, Mai Chi, Zhou, Putian & Cox, Rebecca Jane (2015). Induction of local secretory IgA and multifunctional CD4+ T-helper cells following intranasal immunization with a H5N1 whole inactivated influenza virus vaccine in BALB/c mice. Scandinavian Journal of Immunology. ISSN 0300-9475. 81(5) p 305-317. doi:
10.1111/sji.12288

Panapasa, Jack Alwin, Cox, Rebecca Jane, Mohn, Kristin Greve Isdahl, Aqrawi, Lara Adnan & Brokstad, Karl Albert (2015). The expression of B & T cell activation markers in children’s tonsils following live attenuated influenza vaccine. Human Vaccines & Immunotherapeutics. ISSN 2164-5515. 11(7) p 1663-1672. doi:
10.1080/21645515.2015.1032486

Aqrawi, Lara Adnan (2014). B cell specificity and pattern in primary Sjögren’s syndrome. Universitetet i Bergen. ISBN 978-82-308-2923-3.
FULLTEKST

Aqrawi, Lara Adnan, Kvarnström, Marika, Brokstad, Karl Albert, Jonsson, Roland, Skarstein, Kathrine & Wahren-Herlenius, Marie (2014). Ductal epithelial expression of Ro52 correlates with inflammation in salivary glands of patients with primary Sjögren's syndrome. Clinical and Experimental Immunology. ISSN 0009-9104. 177(1) p 244-252. doi:
10.1111/cei.12341

Aqrawi, Lara Adnan, Skarstein, Kathrine, Øijordsbakken, Gunnvor & Brokstad, Karl Albert (2013). Ro52- and Ro60-specific B cell pattern in the salivary glands of patients with primary Sjögren's syndrome. Clinical and Experimental Immunology. ISSN 0009-9104. 172(2) p 228-237. doi:
10.1111/cei.12058

Aqrawi, Lara Adnan, Skarstein, Kathrine, Bredholt, Geir, Brun, Johan G & Brokstad, Karl Albert (2012). Autoantigen-specific memory B cells in primary Sjögren's syndrome. Scandinavian Journal of Immunology. ISSN 0300-9475. 75(1) p 61-68. doi:
10.1111/j.1365-3083.2011.02625.x

Aqrawi, Lara Adnan, Brokstad, Karl Albert, Jakobsen, Kjerstin, Jonsson, Roland & Skarstein, Kathrine (2012). Low number of memory B cells in the salivary glands of patients with primary Sjögren's syndrome. Autoimmunity. ISSN 0891-6934. 45(7) p 547-555. doi:
10.3109/08916934.2012.712170
Dissemination
Tashbayev, Behzod, Chen, Xiangjun, Utheim, Øa, Rusthen, Shermin, Young, Alix, Herlofson, Bente Brokstad, Hove, Lene Hystad, Singh, Preet Bano, Rykke, Morten, Aqrawi, Lara Adnan, Utheim, Tor Paaske, Garen, Torhild Oddveig, Palm, Øyvind & Jensen, Janicke Liaaen (2018). Primary Sjögren´s Syndrome and Non-Sjögren´s Sicca Syndrome Patients; unexpected differences in symptoms and findings of dry eye disease, dry mouth, and oral health related quality of life .
Hynne, Håvard, Tashbayev, Behzod, Young, Alix, Herlofson, Bente Brokstad, Hove, Lene Hystad, Rykke, Morten, Aqrawi, Lara Adnan, Chen, Xiangjun, Utheim, Øygunn Aass, Palm, Øyvind, Aass, Hans Christian Dalsbotten, Reppe, Sjur, Utheim, Tor Paaske & Jensen, Janicke Liaaen (2018). Evaluation of Dry Eye Disease, Oral Dryness and Inflammatory Cytokines in Primary Sjögren´s Syndrome.
Langeland, Øystein, Tashbayev, Behzod, Rusthen, Shermin, Young, Alix, Herlofson, Bente Brokstad, Hove, Lene Hystad, Singh, Preet Bano, Rykke, Morten, Aqrawi, Lara Adnan, Chen, Xiangjun, Utheim, Øygunn Aass, Utheim, Tor Paaske, Palm, Øyvind & Jensen, Janicke Liaaen (2018). Comparative Ocular and Oral Findings in Sicca Complex.
Tashbayev, Behzod, Rusthen, Shermin, Chen, X, Utheim, Tor Paaske, Utheim, Øygunn Aass, Young, Alix, Herlofson, Bente Brokstad, Aqrawi, Lara Adnan, Rykke, Morten, Hove, Lene Hystad, Palm, Øyvind & Jensen, Janicke Liaaen (2017). Dry Mouth and Dry Eye Examinations of a Norwegian Cohort of Primary Sjögren´s Syndrome Patients.
Young, Alix, Rusthen, Shermin, Aqrawi, Lara Adnan, Rykke, Morten, Hove, Lene Hystad, Herlofson, Bente Brokstad, Singh, Preet Bano, Palm, Øyvind & Jensen, Janicke Liaaen (2016). Dental health status of patients diagnosed with primary Sjögren's Syndrome.
Hove, Lene Hystad, Aqrawi, Lara Adnan, Rusthen, Shermin, Young, Alix, Rykke, Morten, Herlofson, Bente Brokstad, Singh, Preet Bano, Palm, Øyvind, Utheim, Tor Paaske & Jensen, Janicke Liaaen (2016). Establishment of a Dry Mouth Clinic at the Faculty of Dentistry, University of Oslo, Norway.
Rusthen, Shermin, Singh, Preet Bano, Young, Alix, Aqrawi, Lara Adnan, Rykke, Morten, Hove, Lene Hystad, Herlofson, Bente Brokstad, Palm, Øyvind & Jensen, Janicke Liaaen (2016). Oral quality of life, salivary, gustatory and olfactory status in patients with primary Sjögren’s syndrome.
Jensen, Janicke Liaaen, Utheim, Øygunn Aass, Chen, Xiangjun, Thiede, Bernd, Aqrawi, Lara Adnan, Rusthen, Shermin, Young, Alix, Utheim, Tor Paaske & Galtung, Hilde (2016). Searching for Disease Biomarkers for Primary Sjögren’s Syndrome Based on Oral and Ocular Patient Examinations.
Skarstein, Kathrine, Aqrawi, Lara Adnan, Jonsson, Roland & Jensen, Janicke Liaaen (2014). Adipose Tissue is Prominent in Salivary glands of Sjögren’s syndrome Patients and Appears to Influence the Autoimmune Microenvironment in these Organs.

Lara Adnan Aqrawi

Employee details

Research

Scientific Publications

Dissemination